{"id":11073,"date":"2024-01-08T15:49:53","date_gmt":"2024-01-08T12:49:53","guid":{"rendered":"https:\/\/tlab.com.tr\/platelet-rich-plasma-administration-to-the-lower-anterior-vaginal-wall-to-improve-female-sexuality-satisfaction-copy-copy\/"},"modified":"2025-02-06T14:03:53","modified_gmt":"2025-02-06T11:03:53","slug":"factors-affecting-the-features-of-platelet-rich-plasma-in-patients-with-knee-osteoarthritis","status":"publish","type":"post","link":"https:\/\/tlab.com.tr\/en\/factors-affecting-the-features-of-platelet-rich-plasma-in-patients-with-knee-osteoarthritis\/","title":{"rendered":"Factors affecting the features of platelet-rich plasma in patients with knee\u00a0osteoarthritis"},"content":{"rendered":"

ABSTRACT <\/strong><\/p>\n

Objective:<\/strong> The aim of this study was to present an analysis of platelet-rich plasma obtained from patients with knee osteoarthritis and reveal the factors affecting its features.<\/p>\n

Methods:<\/strong> A total of 62 patients (mean age: 56.68 \u00b1 7.13 years) with symptomatic knee osteoarthritis were included in this study. Age (years), gender, height (m), weight (kg), body mass index (kg\/m2 ), duration of symptoms, smoking status, smoking index, general health status, and physical activity scores were recorded. Whole blood and platelet-rich plasma cell counts were performed with a hematology analyzer. White blood cell, red blood cell, and platelet counts were recorded. According to the dose of injected platelets, efficiency of the procedure, purity of platelet-rich plasma, and activation classification, dose of platelets, efficiency of the procedure (platelet recovery rate, %), and purity of the obtained platelet-rich plasma product (relative composition in platelets, %) were calculated. Correlation analysis between the features of platelet-rich plasma and the patient-related variables, including age, gender, body mass index, smoking status, smoking index, presence of other health conditions, physical activity scores, duration of symptoms, and pain levels, was performed.<\/p>\n

Results:<\/strong> Dose of injected platelets, efficiency of the procedure, purity of platelet-rich plasma, and activation analysis showed that the dose of injected platelets was 3.25 billion, the efficiency of the process was 77%, and the purity rate of the platelet-rich plasma was 98.4%. Platelet-rich plasma platelet count was correlated with whole blood platelet count (r=0.81, P < .001), whole blood white blood cell count (r=0.39, P=.002), smoking status (r=0.56, P=.03), smoking index (r=\u22120.63, P=.002), and the presence of hypertension (r=\u22120.31, P=.04). Platelet-rich plasma white blood cell and purity of platelet-rich plasma were correlated with the smoking status of the patients (r=0.52, P=.01; r=0.64, P = .003, respectively).<\/p>\n

Conclusion:<\/strong> This study has demonstrated that high dose and very pure platelet-rich plasma with medium efficiency was yielded with this platelet-rich plasma preparation procedure; whole blood platelet count, the presence of hypertension, and the smoking status of patients affect the features of the obtained platelet-rich plasm<\/p>\n\n\n

\n
Click here to read<\/a><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"

ABSTRACT Objective: The aim of this study was to present an analysis of platelet-rich plasma obtained from patients with knee osteoarthritis and reveal the factors affecting its features. Methods: A total of 62 patients (mean age: 56.68 \u00b1 7.13 years) with symptomatic knee osteoarthritis were included in this study. Age (years), gender, height (m), weight (kg), body mass index (kg\/m2 ), duration of symptoms, smoking status, smoking index, general health status, and physical activity scores were recorded. Whole blood and platelet-rich plasma cell counts were performed with a hematology analyzer. White blood cell, red blood cell, and platelet counts were recorded. According to the dose of injected platelets, efficiency of the procedure, purity of platelet-rich plasma, and activation classification, dose of platelets, efficiency of the procedure (platelet recovery rate, %), and purity of the obtained platelet-rich plasma product (relative composition in platelets, %) were calculated. Correlation analysis between the features of platelet-rich plasma and the patient-related variables, including age, gender, body mass index, smoking status, smoking index, presence of other health conditions, physical activity scores, duration of symptoms, and pain levels, was performed. Results: Dose of injected platelets, efficiency of the procedure, purity of platelet-rich plasma, and activation analysis showed that the dose of injected platelets was 3.25 billion, the efficiency of the process was 77%, and the purity rate of the platelet-rich plasma was 98.4%. Platelet-rich plasma platelet count was correlated with whole blood platelet count (r=0.81, P < .001), whole blood white blood cell count (r=0.39, P=.002), smoking status (r=0.56, P=.03), smoking index (r=\u22120.63, P=.002), and the presence of hypertension (r=\u22120.31, P=.04). Platelet-rich plasma white blood cell and purity of platelet-rich plasma were correlated with the smoking status of the patients (r=0.52, P=.01; r=0.64, P = .003, respectively). Conclusion: This study has demonstrated that high dose and very pure platelet-rich plasma with medium efficiency was yielded with this platelet-rich plasma preparation procedure; whole blood platelet count, the presence of hypertension, and the smoking status of patients affect the features of the obtained platelet-rich plasm<\/p>","protected":false},"author":1,"featured_media":11075,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[58,99,101],"tags":[],"class_list":["post-11073","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-akademik-makaleler","category-orthopedics-and-traumatology","category-physical-medicine-and-rehabilitation"],"views":109,"_links":{"self":[{"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/posts\/11073","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/comments?post=11073"}],"version-history":[{"count":2,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/posts\/11073\/revisions"}],"predecessor-version":[{"id":11083,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/posts\/11073\/revisions\/11083"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/media\/11075"}],"wp:attachment":[{"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/media?parent=11073"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/categories?post=11073"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/tags?post=11073"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}