{"id":2399,"date":"2023-04-25T08:15:15","date_gmt":"2023-04-25T05:15:15","guid":{"rendered":"https:\/\/tlab.com.tr\/?p=2399"},"modified":"2025-02-06T14:19:24","modified_gmt":"2025-02-06T11:19:24","slug":"ovarian-reserve-parameters-and-ivf-outcomes-in-510-women-with-poor-ovarian-response-por-treated-with-intraovarian-injection-of-autologous-platelet-rich-plasma-prp","status":"publish","type":"post","link":"https:\/\/tlab.com.tr\/en\/ovarian-reserve-parameters-and-ivf-outcomes-in-510-women-with-poor-ovarian-response-por-treated-with-intraovarian-injection-of-autologous-platelet-rich-plasma-prp\/","title":{"rendered":"Ovarian reserve parameters and IVF outcomes in 510 women with poor ovarian response (POR) treated with intraovarian injection of autologous platelet rich plasma (PRP)"},"content":{"rendered":"<p>The aim of the current study was to characterize ovarian reserve parameters and IVF outcomes in women with a history of poor ovarian response (POR) treated with intraovarian injection of autologous platelet rich plasma (PRP). Reproductive age women (N=510; age range 30-45yo) diagnosed with POR based on Poseidon criteria were included in the study. PRP treatment resulted in higher AFC, higher serum AMH, lower serum FSH, and a higher number of mature oocytes and cleavage and blastocyst stage embryos. After PRP injection, 22 women (4.3%) conceived spontaneously, 14 (2.7%) were lost to follow up, and 474 (92.9%) attempted IVF. Among women who attempted IVF, 312 (65.8%) generated embryos and underwent embryo transfer, 83 (17.5%) achieved a pregnancy, and 54 (11.4%) achieved sustained implantation\/live birth (SI\/LB). In total, of the 510 women with POR and mean age of 40.3, PRP resulted in improvement of ovarian reserve parameters, a pregnancy rate of 20.5% and SI\/LB rate of 12.9%.<\/p>\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-16018d1d wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/doi.org\/10.18632\/aging.203972\" target=\"_blank\" rel=\"noreferrer noopener\">Click here to read<\/a><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>The aim of the current study was to characterize ovarian reserve parameters and IVF outcomes in women with a history of poor ovarian response (POR) treated with intraovarian injection of autologous platelet rich plasma (PRP). Reproductive age women (N=510; age range 30-45yo) diagnosed with POR based on Poseidon criteria were included in the study. PRP treatment resulted in higher AFC, higher serum AMH, lower serum FSH, and a higher number of mature oocytes and cleavage and blastocyst stage embryos. After PRP injection, 22 women (4.3%) conceived spontaneously, 14 (2.7%) were lost to follow up, and 474 (92.9%) attempted IVF. Among women who attempted IVF, 312 (65.8%) generated embryos and underwent embryo transfer, 83 (17.5%) achieved a pregnancy, and 54 (11.4%) achieved sustained implantation\/live birth (SI\/LB). In total, of the 510 women with POR and mean age of 40.3, PRP resulted in improvement of ovarian reserve parameters, a pregnancy rate of 20.5% and SI\/LB rate of 12.9%.<\/p>","protected":false},"author":1,"featured_media":2402,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[58,80],"tags":[],"class_list":["post-2399","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-akademik-makaleler","category-ivf"],"views":80,"_links":{"self":[{"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/posts\/2399","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/comments?post=2399"}],"version-history":[{"count":3,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/posts\/2399\/revisions"}],"predecessor-version":[{"id":11402,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/posts\/2399\/revisions\/11402"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/media\/2402"}],"wp:attachment":[{"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/media?parent=2399"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/categories?post=2399"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/tags?post=2399"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}