{"id":2530,"date":"2023-04-26T17:50:54","date_gmt":"2023-04-26T14:50:54","guid":{"rendered":"https:\/\/tlab.com.tr\/?p=2530"},"modified":"2025-02-06T14:12:12","modified_gmt":"2025-02-06T11:12:12","slug":"management-of-retinitis-pigmentosa-via-platelet-rich-plasma-or-combination-with-electromagnetic-stimulation-retrospective-analysis-of-one-year-results","status":"publish","type":"post","link":"https:\/\/tlab.com.tr\/en\/management-of-retinitis-pigmentosa-via-platelet-rich-plasma-or-combination-with-electromagnetic-stimulation-retrospective-analysis-of-one-year-results\/","title":{"rendered":"Management of Retinitis Pigmentosa via Platelet Rich Plasma or Combination with Electromagnetic Stimulation: Retrospective Analysis of One-year Results"},"content":{"rendered":"<p><span style=\"font-size: revert; letter-spacing: 0px;\">This research investigates whether the natural progression rate of Retinitis pigmentosa can be reduced by applying subtenon autologous platelet-rich plasma alone or in combination with retinal electromagnetic stimulation, and it has been concluded that PRP can more effectively slow down photoreceptor loss when repeated as support injections and combined with retinal electromagnetic stimulation.<\/span><\/p>\n<div id=\"main\" class=\"sidebar-none sidebar-divider-vertical\">\n<div class=\"wf-wrap\">\n<div class=\"wf-container-main\">\n<div id=\"content\" class=\"content\" role=\"main\">\n<article id=\"post-3843\" class=\"single-postlike post-3843 post type-post status-publish format-standard category-opthalmology-3 category-yayin tag-bioinspired-hydrogel-coating-2 tag-methacryloyl-gelatin-2 tag-methacryloyl-mucin-2 tag-polypropylene-mesh-2 tag-prp-2 tag-university-politehnica-of-bucharest-2 category-96 category-114 description-off\">\n<div class=\"entry-content\">\n<section class=\"wpb-content-wrapper\">\n<div class=\"vc_row wpb_row vc_row-fluid\">\n<div class=\"wpb_column vc_column_container vc_col-sm-12\">\n<div class=\"vc_column-inner\">\n<div class=\"wpb_wrapper\">\n<div id=\"ultimate-heading-22426447b1826c697\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-22426447b1826c697 uvc-934  uvc-heading-default-font-sizes\" data-hspacer=\"line_only\" data-halign=\"left\">\n<div class=\"uvc-sub-heading ult-responsive\" data-ultimate-target=\".uvc-heading.ultimate-heading-22426447b1826c697 .uvc-sub-heading \" data-responsive-json-new=\"{&quot;font-size&quot;:&quot;&quot;,&quot;line-height&quot;:&quot;&quot;}\">\n<p><i><strong>Abstract:<\/strong><br>\nPurpose To investigate whether the natural progression rate of retinitis pigmentosa can be decreased with subtenon autologous platelet rich plasma application alone or combination with retinal<br>\nelectromagnetic stimulation.<br>\nMaterial and methods The study includes retrospective analysis of 60 retinitis pigmentosa patients. Patients constitute 3 groups with similar demographic characteristics. The combined management group consists of 20 retinitis pigmentosa patients (40 eyes) who received combined retinal electromagnetic stimulation and subtenon platelet rich plasma as Group1; The subtenon platelet rich plasma-only group consisted of 20 retinitis pigmentosa patients (40 eyes) as Group2; The natural course (control) group consists of 20 retinitis pigmentosa patients (40 eyes) who did not receive any treatment were classified as Group3. Horizontal and vertical ellipsoid zone width, fundus perimetry deviation index and best corrected visual acuity changes were compared within and between groups after one year follow up period.<br>\nResults Horizontal ellipsoid zone percentage changes were detected +1 % in Group1, -2.85% in Group2, -9.36% in Group3 (\u0394p 1&gt;2&gt;3). Vertical ellipsoid zone percentage changes were detected +0.34 % in Group1, -3.05% in Group2, -9.09% in Group3 (\u0394p 1&gt;2&gt;3). Fundus perimetry deviation index percentage changes were detected +0.05% in Group1, -2.68% in Group2 and -8.78% in Group3 (\u0394p 1&gt;2&gt;3).<br>\nConclusion Platelet-rich plasma is a good source of growth factors, but its half-life is 4-6 months. Subtenon autologous platelet rich plasma might more effectively slow down photoreceptor loss when repeated as booster injections and combined with retinal electromagnetic stimulation.<\/i><\/p>\n<\/div>\n<\/div>\n<div class=\"vc_btn3-container vc_btn3-inline vc_custom_1623072280408\"><a class=\"vc_general vc_btn3 vc_btn3-size-md vc_btn3-shape-rounded vc_btn3-style-modern vc_btn3-color-warning\" title=\"\" href=\"https:\/\/stemcellres.biomedcentral.com\/articles\/10.1186\/s13287-020-01870-w\" target=\"_blank\" rel=\"noopener\">View The Full Text<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<\/div>\n<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-16018d1d wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/stemcellres.biomedcentral.com\/articles\/10.1186\/s13287-020-01870-w\" target=\"_blank\" rel=\"noreferrer noopener\">Click here to read<\/a><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>This research investigates whether the natural progression rate of Retinitis pigmentosa can be reduced by applying subtenon autologous platelet-rich plasma alone or in combination with retinal electromagnetic stimulation, and it has been concluded that PRP can more effectively slow down photoreceptor loss when repeated as support injections and combined with retinal electromagnetic stimulation. Abstract: Purpose To investigate whether the natural progression rate of retinitis pigmentosa can be decreased with subtenon autologous platelet rich plasma application alone or combination with retinal electromagnetic stimulation. Material and methods The study includes retrospective analysis of 60 retinitis pigmentosa patients. Patients constitute 3 groups with similar demographic characteristics. The combined management group consists of 20 retinitis pigmentosa patients (40 eyes) who received combined retinal electromagnetic stimulation and subtenon platelet rich plasma as Group1; The subtenon platelet rich plasma-only group consisted of 20 retinitis pigmentosa patients (40 eyes) as Group2; The natural course (control) group consists of 20 retinitis pigmentosa patients (40 eyes) who did not receive any treatment were classified as Group3. Horizontal and vertical ellipsoid zone width, fundus perimetry deviation index and best corrected visual acuity changes were compared within and between groups after one year follow up period. Results Horizontal ellipsoid zone percentage changes were detected +1 % in Group1, -2.85% in Group2, -9.36% in Group3 (\u0394p 1&gt;2&gt;3). Vertical ellipsoid zone percentage changes were detected +0.34 % in Group1, -3.05% in Group2, -9.09% in Group3 (\u0394p 1&gt;2&gt;3). Fundus perimetry deviation index percentage changes were detected +0.05% in Group1, -2.68% in Group2 and -8.78% in Group3 (\u0394p 1&gt;2&gt;3). Conclusion Platelet-rich plasma is a good source of growth factors, but its half-life is 4-6 months. Subtenon autologous platelet rich plasma might more effectively slow down photoreceptor loss when repeated as booster injections and combined with retinal electromagnetic stimulation. View The Full Text<\/p>","protected":false},"author":1,"featured_media":2532,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[58,94],"tags":[],"class_list":["post-2530","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-akademik-makaleler","category-ophthalmology"],"views":139,"_links":{"self":[{"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/posts\/2530","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/comments?post=2530"}],"version-history":[{"count":2,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/posts\/2530\/revisions"}],"predecessor-version":[{"id":9818,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/posts\/2530\/revisions\/9818"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/media\/2532"}],"wp:attachment":[{"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/media?parent=2530"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/categories?post=2530"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tlab.com.tr\/en\/wp-json\/wp\/v2\/tags?post=2530"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}